Searchable abstracts of presentations at key conferences in endocrinology

ea0038p199 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2015

Evidence for improved mitochondrial efficiency in adipose tissue of T2DM women after malabsorptive but not restrictive bariatric surgery

Martinez de la Escalera Lucia , Jackisch Laura , Kyrou Ioannis , Vrbikova Jana , Hainer Vojtech , Fried Martin , Sramkova Petra , Piya Milan , Kumar Sudhesh , Tripathi Gyanendra , McTernan Philip

Aims/hypothesis: Genetic and functional defects in mitochondria are linked with phenotypes of obesity, hypercholesterolemia, and type 2 diabetes (T2DM). However, the impact on mitochondria during surgery-induced metabolic recovery is unknown. We therefore studied the effect of restrictive versus malabsorptive bariatric procedures on indicators of mitochondrial efficiency and control of biogenesis/function.Methods: Forty-three morbidly obese, T2DM consent...